Familial occurrence of diminished pancreatic amylase in serum--a "silent" Amy-2 allelic variant?
نویسندگان
چکیده
We describe a family of 32 subjects, including two healthy siblings without detectable pancreatic amylase in serum and five healthy relatives (one of them a sister) exhibiting subnormal pancreatic amylase activities. Comparisons of immunoreactive amylase concentrations with the corresponding amylase activities may justify the assumption of a "silent" Amy-2 allelic variant.
منابع مشابه
Selective deficiency of pancreatic amylase.
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Bacillus licheniformis RM44 was isolated from hot spring near Karachi and screened forthe production of extracellular amylase Amy RM44. Amy RM44 was purified to homogeneityon a single step by affinity chromatography using insoluble corn starch. The molecular weightof Amy RM44 was estimated to be 66 kDa by SDS–PAGE and zymographic analysis. Nine foldpurification was achieved with the specific ac...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 34 7 شماره
صفحات -
تاریخ انتشار 1988